Erythema multiforme is divided into major and minor forms and is now regarded as distinct from Stevens–Johnson syndrome (SJS) and toxic epidermal. dermal necrolysis, where erythema multiforme minor is the mildest type .. Gavaldá-Esteve C, Murillo-Cortés J, Poveda-Roda R. Eritema multiforme. Revisión y. Find out about erythema multiforme, a skin reaction that usually causes a rash for a few weeks.

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J Clin Aesthet Dermatol. Definition NCI A systemic, serious, and life-threatening disorder characterized by lesions in the skin and mucous membranes that may lead to necrosis.

Although the full mechanism is not understood, it is in part due to a type IV hypersensitivity immune response, mediated by T lymphocytes. Typically in erythema multiforme, few multicorme hundreds of skin lesions erupt within a hour period.

The condition varies from a mild, self-limited rash E. In EM minor, lesions often present as papules, which might enlarge and eventually form jinor typical target lesion with erythema surrounding an area of central clearing.

Mycoplasma pneumonia a lung infection caused by the bacteria Mycoplasma pneumoniae is the next most common trigger. Occasionally, doctors won’t know what caused the rash to develop, but still can help someone heal. Dusky erythema or Vesicle Middle: This article has been cited by other articles in PMC.

The first line of treatment for EM is removal of the inciting factor when possible.

Erythema multiforme – Wikipedia

Related Bing Images Extra: Erythema multiformw is a hypersensitivity reaction usually triggered by infections, most commonly herpes simplex virus HSV. There may be residual mottled skin discolouration. Disease or Syndrome T May More on this topic for: Erythema multiforme on the hands Erythema multiforme, circular lesions – hands Erythema multiforme, target lesions on the palm Erythema multiforme on the leg Erythema mulfiforme on the hand Exfoliation following erythroderma.


Aphthous stomatitis oral candidiasis lichen planus leukoplakia pemphigus vulgaris mucous membrane pemphigoid cicatricial pemphigoid herpesvirus coxsackievirus syphilis systemic histoplasmosis squamous-cell carcinoma.

Definition NCI A hypersensitivity reaction characterized by the sudden appearance of symmetrical cutaneous and mucocutaneous macular or papular lesions which evolve into lesions with bright red borders target lesions.

Erythema Multiforme Major

With epidermal involvement Eczematous contact dermatitis atopic dermatitis seborrheic dermatitis stasis dermatitis lichen simplex chronicus Darier’s disease glucagonoma syndrome langerhans cell histiocytosis lichen sclerosus pemphigus foliaceus Wiskott—Aldrich syndrome Zinc deficiency. Labs No lab tests are specific for Stevens Johnson Syndrome. Mucosal lesions consist of swelling and redness with blister formation.

You’ll be asked about your medical history, such as recent infections or medicines you’ve taken. There are usually no prodromal symptoms in erythema multiforme minor.

Currently, systemic steroids are not recommended for EM minor; however, topical steroids might be of benefit. Do you have questions about the effects of drugs, chemicals, radiation, or infections in children? Males affected more often than females.

EM major often starts with a fever and joint aches. Br J Oral Maxillofac Surg. Current recommendations suggest not to treat Reitema minor with systemic steroids and that topical steroids might be of benefit. Page Contents Page Contents If you take any of these medicines and notice what looks like an erythema multiforme rash starting, call your doctor but don’t stop taking your medicine unless the doctor suggests it.

Related links to external sites from Bing. Definition CHV An exfoliative skin disease caused by a toxic reaction to drugs, infections, and substance exposure. The lesions may appear anywhere mminor the body but they occur more commonly in the palms, soles, dorsum of the hands, and extensor surfaces.

Erythema multiforme

Other clinicians and researchers argue against use of systemic steroids, suggesting that steroid treatment might increase recovery time, as well as increase the risk of infections and other complications. However the lips are often swollen, especially in erythema multiforme major. Lesions may be at various stages of development with both typical and atypical targets present at the same time. Epub Sep 4.


Search Bing for all related images. Urticaria and erythema L50—L54, Definition NCI A systemic, serious, and life-threatening disorder characterized by erythematous mior necrotic lesions in the skin and mucous membranes that are associated with bullous detachment of the epidermis.

To help figure out why you got the rash, your doctor will ask questions — like whether you’ve had any recent infections or what medications you’re taking. Erythema annulare centrifugum Erythema marginatum Erythema migrans Erythema gyratum repens. The rash is also more macular than in EM. Eritena erythema multiforme major, one or more mucous membranes are typically affected, most often the oral mucosa:.

She’d heard that Lyme disease can cause eriitema target-shaped rash, so she and her mom made an appointment to see the doctor. It is considered a continuum of Toxic Epidermal Necrolysis. The epidermal and mucous membranes detachment leads to sepsis and may be fatal. Epidermal wart callus seborrheic keratosis acrochordon molluscum contagiosum actinic keratosis squamous-cell carcinoma basal-cell carcinoma Merkel-cell carcinoma nevus sebaceous trichoepithelioma.

The lesions usually appear in the hands, feet, extremities, and face. Sometimes blisters develop and quickly break to form erosions and ulcers. If you have any concerns with your skin or its treatment, see a dermatologist for advice. Other tests may be done looking for infections commonly seen in association with erythema multiforme, such as mycoplasma.

However, erythema multiforme major may be preceded by mild symptoms such as fever or chills, weakness or painful joints. Erythemas Herpes simplex virus-associated diseases.