LUPUS TUMIDUS PDF

Lupus tumidus is considered a rare subtype of chronic cutaneous lupus erythematosus, characterized by erythema and bright urticarial erythematous- violaceous. Tumid lupus erythematosus (TLE), also known as lupus erythematosus tumidus, is a highly photosensitive form of cutaneous lupus erythematosus (cutaneous. MalaCards based summary: Lupus Erythematosus Tumidus, also known as intermittent cutaneous lupus, is related to lupus erythematosus and discoid lupus .

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Lupys cutaneous lupus erythematosus. Further systemic manifestations, such as renal, central nervous system, or lung involvement, have not yet manifested in any of the 40 patients during our study after up to 15 years.

Med Cutan Ibero Lat Am. Further immunosuppression will inevitably lead to a higher risk of infection and considering her age, there is a high probability of developing a serious infection in her lifetime. Articles which use infobox templates with no data rows Infobox medical condition new All stub articles.

We suggest systemic antimalarial drugs as the treatment of choice for lupus tumidus. The mean age of the entire group, when reviewed for the study inwas Because of the latency period in development luupus positive phototest reactions, it may be difficult for patients to link sun exposure with their skin lesions.

During the past 15 years, we have investigated clinical, histological, photobiological, and laboratory features of 40 patients with LET.

Support Center Support Center. Interestingly, the mainstay of treatment for LET, in the limited case reports and series that exist, is with antimalarial drugs, which our patient had already been taking for SLE.

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Cutaneous lupus erythematosus

The patient responded well to treatment and we observed no new lesions. This case exemplifies the need for complete disease characterization, evidence-based treatment, and a multidisciplinary approach.

Specific features of acute cutaneous LE may include:. A mildly elevated creatinine level from Although the patients are clinically identified by a characteristic type of skin lesion, LET has been reported previously in the literature in only a few cases.

Lupus Erythematosus Tumidus: A Unique Disease Entity

Right upper arm with blanching inflamed plaques with raised borders. Exam was remarkable for blanching, inflamed plaques with raised borders, proximally on both arms, cheeks, and temples with coalescing of lesions Figure 1 and Figure 2. Lupus tumidus was first described by Gougerot and Bournier in Lupus erythematosus tumidus LETa rare subset of chronic cutaneous LE CCLEwas first mentioned by Gougerot and Burnier 6 in in a lupue of 2 patients with erythematous, infiltrated, nonscarring plaques on the face.

Despite being first described inthere are few case reports in the current literature describing this disease and even fewer that discuss treatment.

Histological features include perivascular and periadnexal lymphocytic infiltration and interstitial mucin deposition.

Laboratory abnormalities or substantial ocular toxic effects caused by antimalarials did not occur in any of the patients with LET. Epub Apr She was referred to Dermatology for an intermittent pruritic facial eruption that was clinically and histologically consistent with LET. This page was last edited on 1 Julytumisus Report of 40 Cases. A punch biopsy of her right upper extremity revealed a superficial and deep periadnexal llupus interstitial infiltrate Figure 3.

Updated in January Since its first description inLET has been documented rarely in the literature, and its clinical importance has lupue been fully appreciated. Patients, materials, and methods. The infiltrate was composed of lymphocytes, histiocytes, plasma cells, and a few scattered neutrophils.

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Total hemolytic complement CH50 was measured using the photometer, and lupus anticoagulant was evaluated by kaolin clotting time KCT. Chronic cutaneous LE causes facial deformity and scarring. The main difference between the diseases is the clinical manifestation. Purchase access Subscribe to the journal. Purchase access Subscribe to JN Learning for one year. LET is a photosensitive skin disease that is characterized by succulent, edematous, non-scarring plaques.

Tumidue biopsy may be diagnostic, showing a lichenoid tissue reaction and features specific to the kind of cutaneous LE.

Lupus tumidus: a report of two cases

It may be accompanied by antiphospholipid syndrome. Photograph of face showing blanching inflamed plaques with raised borders and coalescing of lesions. She complained of mild pruritis and tenderness.

Received Jul 17; Accepted Oct By using this site, you agree to the Terms of Use and Privacy Policy. We report two cases of lupus tumidus, which deserve attention for their low frequency in the literature, in addition to their relevance as a differential diagnosis among dermatologic disorders.

A general stepwise approach to treatment can be partially extrapolated from Kuhn, et al’s, series of 40 patients from a progressively more systemic and toxic lineation; sunscreen sun exposure avoidancetopical steroid treatment, antimalarial therapy, followed by systemic steroids, and other immunosuppressants.

Verh Dtsch Ges Pathol.