Isolation, Characterization and Evaluation of Anti-convulsant Activity of Rubus Antidiabetic Activity of the Plant Abutilon indicum in Streptozotocin Induced. Abutilon hirtum extract and fractions exhibited anti-inflammatory analgesic, antipyretic and antipyretic activities which may be attributed by the. Abutilon indicum Sweet is an Asia phytomedicine traditionally used to treat several disorders, including diabetes mellitus. However, molecular.

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In the follow-up studies, we examined potential mechanisms underlying the improvement in glucose utilization by the extract. Thus, these data imply that the butanol fraction of A. The needles being rich in resin content is a highly inflammable fuel for igniting forest fires. In fact, it has been known that the extrapancreatic action of glibenclamide has an important role to inhibit glucose production by liver and improve carbohydrate metabolism in diabetes [ 3435 ], and increases glucose disposal acrivity stabilizing GLUT1 protein at the plasma membrane of muscle [ 36 ].

In fact, impairment of insulin action has also been observed in syndromes including inflammatory and chronic infectious diseases in addition to type 2 DM [ 4 ]. We have reported that the phytochemical analysis of the whole plant extract revealed the presence of alkaloids, flavonoids, and tannins [ 11 ].

This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In addition, an attempt was made to identify the class of phytochemicals present in the leaves and also attribute the pharmacological property of the leaves to the particular type of phytochemicals.


Rajesh Garg and V. Insulin resistance is a key feature in type 2 DM as well as in obesity and plays an important pathophysiological role [ 3 ]. The luciferase activity was expressed as a ratio of firefly to renilla luciferase activity.

Volume2,Issue2 – Pharmacognosy Phytochemistry

The leaves of Abutilon indicum Linn. Summary of antidiabetic effects against insulin resistance of A. However, prior to treatment administration day 0basal plasma glucose concentration did not significantly differ between groups.

The methanolic extract was subjected to anticonvulsant activity by MES induced epilepsy and determination of neurotransmitter concentrations in rat brain after induction of epilepsy. The boiling process was repeated twice, and the combined extract was filtered across cotton wool and gauze. Compound II-9, 10 epoxynonacosane have been isolated from the methanolic aerial extract of the Rubus racemosus. Pieces of diaphragms were incubated with various concentrations of the crude extract for 1.

Pharmacognostical Evaluation of Tylophora indica Burm. Originally, TZDs were identified based on their antihyperglycemic activity, but they are also able to improve other abnormalities associated with type 2 diabetes, such as hyperlipidemia, atherosclerosis, hypertension, chronic inflammation and fibrinolytic state.

The plant Cayratia carnosa gagnep.

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The leaves, twigs and roots of A. Pines clearly form the most ecologically and economically significant tree group in the world. Results from other researchers have acyivity that this plant also contains saponins and glycosides [ 10 ].

The filtrate was lyophilized in a freeze dry system resulting in a dark brown powder of In addition all the extracts have shown CNS depressant activity.


Anti-diabetic and analgesic activity of leaves of abutilon indicum

A number of medicinal uses has been reported some important onces are Antioxidant, antihelmintic activity, Hepato-Protective activity, antidiarrhoeal activity, Tumor growth inhibitory activity. With respect to its traditional use, A. Cost of Full Paper: As there is no detailed on the standardisation work reported on stem, the physicochemical parameters, brief study on pharmacological activities and microbial contamination analysis are carried out.

This medicinal plant plays an important role in folk medicine; in Thailand, it has been used as a blood tonic, carminative, antipyretic, anti-cough, diuretic, anti-inflammatory, laxative and antidiabetic [ 12 ], whereas in India and China, it has been used for urinary disease, gonorrhea, jaundice, rheumatism, high fever, mumps, pulmonary tuberculosis, bronchitis, lack of urination and some nervous and ear problems [ 1314 ].

Extracts of the roxburgii were tested for growth inhibitory against bacterial plant pathogens, mosquito. We could not exclude the possibility that butanol fraction affects mRNA stability of those genes, and further studies may require elucidating the molecular mechanism by which butanol fraction affects gene induction during adipogenesis. The presence of narrow rectangular and thick walled epidermimal cells, abufilon and vascular bundles connected to the abaxial epidermis in the lamina, rosette antiriabetic, raphide, petioles without wings etc.

Most plants with antidiabetic properties have been found to contain metabolites such as glycosides, alkaloids and flavonoids [ 9 ].