The effect of hydro-alcoholic celery (Apium graveolens) leaf extract on cardiovascular parameters and lipid profile in animal model of hypertension induced by. Abstract: Apium graveolens (celery) is an edible and traditionally medicinal plant worldwide, among others for the treatment of hypertension. Celery (Apium graveolens L., Apiaceae) is one of the popular aromatic mean arterial blood pressure and heart rate in normotensive and hypertensive rats.

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Luteolin inhibits an endotoxin-stimulated phosphorylation cascade and proinflammatory cytokine production in macrophages. Thymoquinone TQone of the most graveklens and bioactive components in Nigella sativa ‘s seeds, has been identified as the major element in its healing effects Ahmad et al. The hexanic, methanolic, and aqueous-ethanolic extracts were administered intraperitoneally and their effects on BP and heart rate HR were evaluated in comparison with spirnolactone graeolens a diuretic and positive control.

Benefits, adverse effects and drug interactions of herbal therapies with cardiovascular effects. Effect of garlic on cardiovascular disorders.

Antihypertensive Effect of Celery Seed on Rat Blood Pressure in Chronic Administration

Roselle primes the vasorelaxant pathways of both endothelial cells Ajay et al. A combination treatment of danshen and gegen Pueraria hyprrtension was shown to lower blood pressure in SHRs Ng et al.

Protective effects of celery juice in treatments with doxorubicin.

Effects of Crataegus microphylla on vascular dysfunction in streptozotocin-induced diabetic rats. Author information Article notes Copyright and License information Disclaimer.


Phytomedicine 19— Danshen’s most effective components include: Green tea has been reported yraveolens increase CAT antioxidant enzyme while simultaneously blocking AT 1 receptors in streptozotocin-treated rats Thomson et al.

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How to evaluate microvascular organ damage in hypertension: Cardiovascular Diseases and Panax ginseng: Indeed, the lack of sufficient clinical trials constitutes a significant limitation on their use at the present time. A new look at the renin-angiotensin system—focusing on the vascular system.

A voucher specimen was deposited at the Herbarium of Morelos State University. Effects of aqueous celery Apiumgraveolens extract on lipid parameters of rats fed a high fat diet. Dose-dependent induction of endogenous antioxidants in rat heart by chronic administration of garlic.

The same authors also reported BBR’s vasorelaxant activity on KCl-induced contractions using the same models Zhang et al.

CCl 4 -induced hepatotoxicity in Wistar albino rats.

Protective effect of Cymbopogon citratus on hydrogen peroxide-induced oxidative stress in the reproductive system of male rats. Antihypertensive effect of Iranian Crataegus curvisepala Lind.: This is partly due to the supporting clinical trials and epidemiological studies.

Rat coronary arterial rings.

Antihypertensive Effect of Celery Seed on Rat Blood Pressure in Chronic Administration

Support Center Apimu Center. Natural antioxidants and hypertension: Ethyl Acetate extract from A. Elevated blood pressure is categorized into types: Inhibits ERK pathway activation. Negative control group received vehicle saline or paraffin. Coriander fruit exhibits gut modulatory, blood pressure lowering and diuretic activities.

Apigenin, a flavone isolate of A. Nowadays, there are many herbal medicines for management of HTN, for example, garlic, hawthorn, and cayenne pepper. New perspectives on how to discover drugs from herbal medicines: Author contributions All authors contributed to the writing.


Cognitive-enhancing and antioxidant activities of inhaled coriander volatile oil in amyloid beta rat model of Alzheimer’s disease. National Center for Biotechnology InformationU. Crataegus special extract WS causes endothelium-dependent relaxation via a redox-sensitive Src- and Akt-dependent activation of endothelial NO synthase but not via activation of estrogen receptors.

Human umbilical vein endothelial cells. In addition to anti-hypertensive effects, ginseng also plays anti-carcinogenic and antidiabetic roles Choi et al. J Agric Food Chem. The vascular smooth muscle cell in arterial pathology: In the L-NAME-induced hypertension model, the blood pressure decreased after the administration of Crataegus tanacetifolia leaf extract or its isolate, hyperoside.

Anti-hypertensive Herbs and their Mechanisms of Action: Part I

Consumption of Hibiscus sabdariffa L. Constituents of goldthread also act by relaxing arterial tissues through endothelial-dependent and independent routes Affuso et al.

Mechanisms underlying the antihypertensive effects of garlic bioactives. In addition, green tea has the capacity to scavenge superoxides Nakagawa and Yokozawa, in vitro as well as attenuate NAPDH oxidase production Ribaldo et al.

Antihypertensive effect of nuatigeninO-beta-chacotriose from Solanum sisymbriifolium Lam. Table 2 Commonly used antihypertensive plants with vasorelaxant activity.