Insulin lispro protamine is used to reduce high blood sugar levels in patients Insulin lispro protamine is injected under the skin. Humalog Mix KwikPen. HUMALOG é indicado no tratamento de pacientes com diabetes mellitus que necessitam .. médico e leve a embalagem ou bula do medicamento, se possível. 18 abr. B. Humalog Mix 50 Lilly (50% lispro/protamina e 50% lispro). 2,0. .. dicado em bula, o uso combinado de exanatide com.

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Instructions for use and handling To prevent the possible transmission of disease, each pen must be used by one patient only, even if the needle is changed. However, glucose solution must be given intravenously if glucagon is not available or if the patient fails to respond to glucagon. This site uses cookies. Hypoglycaemia may be associated with listlessness, confusion, palpitations, headache, sweating and vomiting.

The advisability of driving should be considered in these circumstances. Insulin requirements and dosage adjustment Insulin requirements may be increased during illness or emotional disturbances. In some studies, reduction of nocturnal hypoglycaemia was associated with increased episodes of daytime hypoglycaemia.

After first use 28 days. Therefore, the requirement for patients to self-inject is that they can read the dose counter on the pen.

Drug Information | The Filipino Doctor

When considering the clinical relevance of these kinetics, it is more appropriate to examine the glucose utilisation curves as discussed in 5. The pharmacokinetics of insulin lispro reflect a compound that is rapidly absorbed, and achieves peak bulw levels 30 to 70 minutes following subcutaneous injection. The number of insulin units is shown in the dose window of the pen regardless of strength and no dose conversion should be done when transferring a patient to a new strength or to a pen with a different dose step.


Posology The dosage should be determined by the physician, according to the requirement of the patient. Exercise taken immediately after a oispro may increase the risk of hypoglycaemia. View our Humalog coupons and hmualog promo offers. Mild hypoglycaemic episodes will respond to oral administration of glucose or other sugar bila saccharated products.

Combination of Humalog with pioglitazone Cases of cardiac failure have been reported when pioglitazone was used in combination with insulin, especially in patients with risk factors for development of cardiac heart failure.

Insulins have no specific overdose definitions because serum glucose concentrations are a result of complex interactions between insulin levels, glucose availability and other metabolic processes.

Glucodynamic differences between insulin lispro and soluble human insulin, as measured during a glucose clamp procedure, were maintained over a wide range of renal function. Subcutaneous administration should be in the upper arms, thighs, buttocks, or abdomen.

Humalog 200 Units/ml KwikPen, solution for injection in pre-filled pen

For the treatment of adults with diabetes mellitus who require insulin for the maintenance of normal glucose homeostasis. It may cause a rash over the whole body, shortness of breath, wheezing, reduction in blood pressure, fast pulse, or sweating. Insulin lispro has a rapid onset of action approximately 15 minutesthus allowing it to be given closer to a meal within zero to 15 minutes of the meal when compared to soluble insulin 30 to 45 minutes before.

Each pre-filled pen contains units of insulin lispro in 3 ml solution. Humalog insulin lispro is used to treat type 1 insulin-dependent diabetes in adults. View Humalog U numalog information, blood sugar testing considerations and common side effects. In patients with type 2 diabetes on maximum doses of sulphonyl urea agents, studies have shown that the addition of insulin lispro significantly reduces HbA1c compared to sulphonyl urea alone.

A few patients who have experienced hypoglycaemic reactions after transfer from animal-source insulin to nula insulin have reported that the liapro warning symptoms of hypoglycaemia were less pronounced or different from those experienced with their previous insulin.


The patient should be given a meal as soon as consciousness is recovered. A consequence of the pharmacodynamics of rapid-acting insulin analogues is that if hypoglycaemia occurs, it may occur earlier after an injection when compared with soluble human insulin.

Insulin lispro maintains more rapid absorption and elimination when compared to soluble human insulin in patients with hepatic impairment.

Do not expose to excessive heat or direct sunlight. This should be kept in mind, if treatment with the combination of pioglitazone and Humalog is considered. Ideal for people with no prescription coverage,or drug is not covered Type I glass cartridges, sealed with halobutyl disc seals and plunger heads and secured with aluminium seals.

Insulin requirements may be increased pispro medicinal lisppro with hyperglycaemic activity, such as oral contraceptives, corticosteroids, or thyroid replacement therapy, danazol, beta 2 stimulants such as ritodrine, salbutamol, terbutaline.

Insulin requirements may be reduced in patients with hepatic impairment due to reduced capacity for gluconeogenesis humwlog reduced insulin breakdown; however, in patients with chronic hepatic impairment, an increase in insulin resistance may lead to increased insulin requirements. Any unused product or waste material should be disposed of in accordance with local requirements.

Qualitative and quantitative composition 3. Eli Lilly Nederland B. Company contact details Eli Lilly and Company Limited.

To bookmark a medicine you must sign up and log in. Sustained carbohydrate intake and observation may be necessary because hypoglycaemia may recur after apparent clinical recovery.